1. Introduction
Prefilled syringe filling stoppering machine, also known as prefilled machine, filling machine, feeding machine, etc., is an advanced equipment used in the pharmaceutical manufacturing industry. It can inject the medicine solution into small bottles or bags through filling pipelines, and fill the required fillers or storage gases into the medicine solution. This article will introduce the principle, process, and function of the machine.
2. Principle
The prefilled syringe filling stoppering machine consists of a material cylinder, needle, motor, gear, etc. The medicine is injected into small bottles or bags through filling pipelines using needles, and the required storage gas or filler is also injected into the medicine through other pipelines.
In this machine, there are mainly three process principles: filling, sealing, and stoppering.
3. Filling
Filling refers to the process of injecting a medicinal liquid into a bottle or bag through a filling pipeline. In this equipment, the injection time is adjusted by setting quantitative dosage, and the needle is controlled for quantitative filling. Due to the high precision of the equipment, the filling process can be quantified very accurately.
4. Sealing
The equipment will automatically seal the bottle or bag at the filling pipeline position. After ensuring that the medication is filled and sealed, the equipment will automatically cut off the injection pipeline and output a "complete" signal.
5. Stoppering
Stoppering refers to the process of adding an appropriate amount of stored gas or filler to a liquid medicine. For example, stored gas can be used to maintain the freshness and shelf life of drugs, and fillers can be used to increase the viscosity of drugs and the stability of pharmaceuticals. Through this equipment, the amount of storage gas or filler added can be strictly controlled to ensure drug quality.
6. The prefilled syringe filling stoppering machine mainly has the following functions:
1)Quantitative filling of bottles:
Fill the medicine solution into the bottles according to the requirements.
2)Quantitative stoppering of bottles:
Improve the quality of traditional Chinese medicine solution in bottles by adding an appropriate amount of filler or gas.
3)Automatic sealing of bottles:
After filling and stoppering are completed, the bottles will be automatically sealed.
4)Automatic control of filling tube:
This equipment can automatically select the thickness of the needle based on the size of the filling volume.
5)Automatic turntable puncture of bottles:
During the operation, the bottles will automatically rotate the turntable to ensure even filling.
7. Conclusion
The prefilled syringe filling stoppering machine is an essential advanced equipment in the pharmaceutical manufacturing industry. Through the operation of the equipment, high-precision quantitative filling can be achieved and more effective control of drug quality and production efficiency can be achieved.