Cartridge Filling Stoppering Capping Machine

Cartridge Filling Production Line

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Tel: 0086-13507449007
E-mail: sales@marya.com.cn

Introduction
Application Industry
Performance Advantages of Cartridge Filling Machines:

The cartridge filling line is composed of an ultrasonic bottle washing machine, an air-drying silicone oil injection integrated machine, a sterilization dryer, and a cartridge stoppering filling capping machine. It can complete complex functions such as spraying water, ultrasonic cleaning, air & water flushing of the inner and outer walls of cartridge bottles, air drying, silicone oil spraying, preheating, drying, and sterilization, heat source removing, cooling, stoppering, filling, capping, etc., realizing automatic production of the whole process. Each machine can be used separately or in a linkage line and is mainly used for the production of cartridge injectables under aseptic conditions in the pharmaceutical industry.

Marya cartridge filling line is mainly used in the biomedical and cosmetics industry, suitable for the filling and production of vaccines, insulin, antibiotics, interferon, anesthesia and sedation and other drugs and hyaluronic acid and other beauty products. The finished product can also be used in ophthalmology, stomatology, ear, orthopedics, gynecology and other medical industries.

1. Wide applicable specifications, large production capacity, high filling accuracy:

Applicable specifications: 1.5-3ml
Production capacity: ~8400 bottles/hour
Number of stoppering heads: 4
Number of filling heads: 8 (divided into two fillings)
Filling accuracy: up to ±1%
Pass rate of plugging: ≥99%
Capping qualification rate: ≥99%

2. Mature technology, using industry-leading high-end technology, stable performance and cost saving:

The whole cartridge filling line meets the requirements of the new GMP, and the bottle cleaning effect meets the new pharmacopoeia standards and requirements;
This filling line is a full servo motor system control model, and the parameters that need to be adjusted can be adjusted on the touch screen;
The advanced electrical control system is adopted, the operating speed can be steplessly regulated, with complete interlocking function, and the operating parameter display screen is displayed centrally;
The heat source of the tunnel hot air circulation oven is evenly distributed, and the heat source removal effect is good;
The sterilizing drying oven is not only suitable for the drying, disinfection and sterilization of ampoules, vials and cartridge bottles, but also for the drying, disinfection and sterilization of other pharmaceutical glass bottles;
Automatic recording of temperature recording and curve chart automatic printing;
Using positioning dial to walk bottles (servo motor driven) to walk 4 bottles at a time, filling positioning is accurate;
The ceramic rotary valve pump (8 sets) is used to fill in 2 times, the first filling is 50-70%, the second time is full filling, and there is a vacuum pumping needle at the mouth of the bottle filled in the second filling, and the excess little liquid is pumped into the recycling bottle through the pumping needle;
The parts in contact with the chemical solution are 316L stainless steel or silicone, and the rest of the surfaces are 304 stainless steel or POM (PE);
Marya cartridge bottle filling line has the function of full line linkage, and the front and rear equipment linkage control;
The use of high-precision color touch display operation monitoring, PLC automatic control, automatic protection, host frequency conversion speed regulation and other control technologies for the production process automatic control and monitoring;

3. A variety of functions are optional, customized according to your needs:

Servo motor controls the filling pump for filling, with high filling accuracy and convenient adjustment;
Optional CIP/SIP system;
The online sterilization function of the cooling section of the tunnel hot air circulation oven;
The equipment has compact structure, with glass door opening protective cover, and can be configured with Open-RABS/Close-RABS isolation protection system and 100-level air purification laminar flow system;
Vacuum filling system can be configured for filling high viscosity products;
According to whether the customer's product is toxic or active, the fully enclosed aseptic isolation (Isolator) system can be configured;